Could smelling food lead to weight gain? - Sabi Tips


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Could smelling food lead to weight gain?

Researchers have uncovered a link between sense of smell and fat burning.A team of researchers has recently made a surprising discovery: mice that cannot smell their food do not gain weight. A new study explores some of the reasons behind this.

Researchers led by Andrew Dillin, a professor of molecular and cell biology at the University of California, Berkeley, were surprised to discover that mice lacking a sense of smell do not gain weight, despite being fed a high-fat diet.

The results of the new study were published in the journal Cell Metabolism, and the findings point to an unexplored link between olfactory neurons and weight gain.As the authors of the research explain, it is known that our sense of smell, together with the olfactory input from the environment, help us to select and appreciate food. The sense of smell and that of taste are heightened before a meal, and they tend to decline immediately afterward.

Also, results of a new study published by JAMA Cardiology add to the evidence of an association between higher body mass index (BMI) and increased risk of cardiometabolic diseases such as hypertension, coronary heart disease, type 2 diabetes.

A connection between higher BMI and cardiometabolic disease risk usually arise from observational studies that are unable to fully account for confounding by shared risk factors. Mendelian randomization (a method of analysis using genetic information) is an approach that partially overcomes these limitations. Using mendelian randomization, Donald M. Lyall, Ph.D., of the University of Glasgow, Scotland, and colleagues conducted a study that included 119,859 participants in the United Kingdom (UK) Biobank (with medical, sociodemographic and genetic data) to examine the association between BMI and cardiometabolic diseases and traits.

Of the individuals in the study, 47 percent were men; average age was 57 years. The researchers found that higher BMI was associated with an increased risk of coronary heart disease, hypertension, and type 2 diabetes, as well as increased systolic and diastolic blood pressure.

These associations were independent of age, sex, alcohol intake, and smoking history.The authors write that the results of this study has relevance for public health policies in many countries with increasing obesity levels. “Body mass index represents an important modifiable risk factor for ameliorating the risk of cardiometabolic disease in the general population.”A limitation of the study was that the sample lacked data on a complete range of potential mediators, such as lipid traits and glucose levels.

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